Dimethyltryptamine (DMT ) is a psychedelic compound found in nearly every living organism including human. The the movie is an investigation into the long undetermined mystery of DMT. When ingested it acts as a psychedelic drug, resulting a short to long psychedelic state depends on the dose. The person undergo this state experience some sort of spiritual realms, a total loose of conventional reality. The famous shamanic Ayahuasca uses DMT rich ingredients too. The documentary deals with a combination of science, spirituality and social matters.